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BIBTEX RIS

A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine

2011; Royal Society of Chemistry; Volume: 47; Issue: 39 Linguagem: Inglês

10.1039/c1cc14653j

ISSN

1364-548X

Autores

Jingyan Ge, Lin Li, Shao Q. Yao,

Tópico(s)

Chemical Synthesis and Analysis

Resumo

Synthesis of the first self-immobilizing, fluorogenic unnatural amino acid that mimics phosphotyrosine (pTyr) is reported. By using solid-phase peptide synthesis, it was subsequently incorporated into peptide-based probes which found applications in bioimaging and fluorescence-activated cell sorting (FACS).

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