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Potential Nonpneumococcal Confounding of PCR-Based Determination of Serotype in Carriage

2012; American Society for Microbiology; Volume: 50; Issue: 9 Linguagem: Inglês

10.1128/jcm.01505-12

1098-660X

María da Gloria Carvalho, Godfrey Bigogo, Muthoni Junghae, Fabiana Cristina Pimenta, Iaci Moura, Alexis Roundtree, Zhongya Li, Laura Conklin, Daniel R. Feikin, Robert F. Breiman, Cynthia G. Whitney, Bernard Beall,

Pneumonia and Respiratory Infections

Monitoring pneumococcal carriage serotype distributions is increasingly used to study pneumococcal biology, disease epidemiology, and vaccine impact. Potentially complicating DNA-based carriage assessment is the well-documented history of genetic recombination between pneumococci and related species