Artigo Produção Nacional

An anti-inflammatory and immunomodulatory polysaccharide from Orbignya phalerata

2001; Elsevier BV; Volume: 72; Issue: 8 Linguagem: Inglês

10.1016/s0367-326x(01)00338-0

ISSN

1873-6971

Autores

Bernadete Pereira da Silva, José Paz Parente,

Tópico(s)

Carbohydrate Chemistry and Synthesis

Resumo

A polysaccharide, a glucan with mean Mr of 1.0×106 (MP1), was isolated from the mesocarp of fruits of Orbignya phalerata. Chemical and spectroscopic studies indicated that MP1 has a highly branched glucan type structure composed of α-(1→4) linked d-glucopyranose residues with (3→4), (4→6), and with (3→6) branching points. MP1 enhanced phagocytosis in vivo and exhibited anti-inflammatory activity.

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