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Spontaneous Feline Hypertension: Clinical and Echocardiographic Abnormalities, and Survival Rate

2003; Wiley; Volume: 17; Issue: 1 Linguagem: Inglês

10.1892/0891-6640(2003)017 2.3.co;2

1939-1676

Valérie Chetboul, Hervé P. Lefebvre, Carine Pinhas, Bernard Clerc, Maya Boussouf, Jean‐Louis Pouchelon,

Cardiovascular Disease and Adiposity

Journal of Veterinary Internal MedicineVolume 17, Issue 1 p. 89-95 Open Access Spontaneous Feline Hypertension: Clinical and Echocardiographic Abnormalities, and Survival Rate Valerie Chetboul, Corresponding Author Valerie Chetboul Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, France Unite de Cardiologie d'Alfort, Ecole Nationale Veterinaire d'Alfort, 7Avenue du Général de Gaulle, 94 704Maisons-Alfort Cedex, France; e-mail: [email protected]Search for more papers by this authorHervé P. Lefebvre, Hervé P. Lefebvre Unité Mixte de Recherches, Physiopathologie et Toxicologie Expérimentales, Ecole Nationale Vétérinaire de Toulouse, Toulouse, FranceSearch for more papers by this authorCarine Pinhas, Carine Pinhas Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorBernard Clerc, Bernard Clerc Unité d'Ophtalmologie, Ecole Nationale Veterinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorMaya Boussouf, Maya Boussouf Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorJean-Louis Pouchelon, Jean-Louis Pouchelon Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this author Valerie Chetboul, Corresponding Author Valerie Chetboul Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, France Unite de Cardiologie d'Alfort, Ecole Nationale Veterinaire d'Alfort, 7Avenue du Général de Gaulle, 94 704Maisons-Alfort Cedex, France; e-mail: [email protected]Search for more papers by this authorHervé P. Lefebvre, Hervé P. Lefebvre Unité Mixte de Recherches, Physiopathologie et Toxicologie Expérimentales, Ecole Nationale Vétérinaire de Toulouse, Toulouse, FranceSearch for more papers by this authorCarine Pinhas, Carine Pinhas Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorBernard Clerc, Bernard Clerc Unité d'Ophtalmologie, Ecole Nationale Veterinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorMaya Boussouf, Maya Boussouf Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this authorJean-Louis Pouchelon, Jean-Louis Pouchelon Unité de Cardiologie d'Alfort, EcoleNationale Vétérinaire d'Alfort, Maisons-Alfort, FranceSearch for more papers by this author First published: 28 June 2008 https://doi.org/10.1111/j.1939-1676.2003.tb01328.xCitations: 97AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Systemic hypertension was diagnosed in 58 of 188 untreated cats referred for evaluation of suspected hypertension-associated ocular, neurologic, cardiorespiratory, and urinary disease, or diseases frequently associated with hypertension (hyperthyroidism and chronic renal failure). Hypertensive cats were significantly older than normotensive subjects (13.0 ± 3.5 years versus 9.6 ± 5.0 years; P < .01), and had a greater prevalence of retinal lesions (48 versus 3%; P < .001), gallop rhythm (16 versus 0%; P < .001), and polyuria-polydipsia (53 versus 29%; P < .01). Blood pressure was significantly higher (P < .001) in cats with retinopathies (262 ± 34 mm Hg) than in other hypertensive animals (221 ± 34 mm Hg). Hypertensive cats had a thicker interventricular septum (5.8 ± 1.7 versus 3.7 ± 0.64 mm; P < .001) and left ventricular free wall (6.2 ± 1.6 versus 4.1 ± 0.51 mm; P < .001) and a reduced diastolic left ventricular internal diameter (13.5 ± 3.2 versus 15.8 ± 0.72 mm; P < .001) than control cats. Left ventricular geometry was abnormal in 33 of 39 hypertensive subjects. No significant difference was found in age or blood pressure at the initial visit between cats that died or survived over a 9-month period after initial diagnosis of hypertension. Mean survival times were not significantly different between hypertensive cats with normal and abnormal left ventricular patterns. Further prospective studies are needed to clearly identify the factors involved in survival time in hypertensive cats. References 1 Kobayashi DL, Peterson ME, Graves TK, et al. Hypertension in cats with chronic renal failure or hyperthyroidism. J Vet Intern Med 1990; 4: 58– 62. 2 Littman MP. 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