Packed capillary liquid chromatography/mass spectrometry using a moving belt interface
1989; Wiley; Volume: 18; Issue: 1 Linguagem: Inglês
10.1002/bms.1200180111
ISSN2376-3868
AutoresAldos C. Barefoot, R. W. Reiser,
Tópico(s)Advanced Chemical Sensor Technologies
ResumoPacked capillary liquid chromatography/mass spectrometry using a moving belt interface is a practical, versatile technique for the identification of unknowns. The low flow rates (1–2 μl min−1) improve the operation of the moving belt and allow direct deposition of eluates from reversed-phase liquid chromatographic columns containing large proportions of water. Column performance and durability is equivalent to that obtained with conventional or microbore liquid chromatographic columns. Techniques have been developed for analyzing dilute solutions with no loss in column performance and for the detection of radiolabeled metabolites. Applications to analyses of polar, thermally labile compounds and environmental samples are presented.
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