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BIBTEX RIS

The Morphological Aspects of Neovaginoplasty Using Oxidized Cellulose Membrane (Interceed®)

2013; Mary Ann Liebert, Inc.; Volume: 29; Issue: 4 Linguagem: Inglês

10.1089/gyn.2011.0098

1557-7724

Luciana Campanatti Crema, Zsuzsanna Ilona Katalin de Jármy Di Bella, Cláudia Cristina Takano, Rodrigo Aquino Castro, Manuel de Jesus Simões, Marair Grácio Ferreira Sartori, Manoel Joâo Batista Castello Girão,

Sexual Differentiation and Disorders

Objective: The purpose of this study was to evaluate the postoperative morphologic aspects of neovaginoplasty by the McIndoe technique with the use of an oxidized cellulose membrane (Interceed®) – an absorbable adhesion barrier – to correct congenital vaginal defects. Design: This study was designed as a prospective study. Patients and Methods: The sample consisted of 10 patients treated at the Department of Urogynecology, Federal University of São Paulo, 7 patients with Mayer–Rokitansky–Küster–Hauser Syndrome, and 3 patients with congenital vaginal atresia. In order to evaluate the epithelization process, monthly biopsies for the first 3 months and then on the 9th month after neovaginoplasty using Interceed, were collected. Results: In all patients, lamina propria rich in blood vessels and epithelioid cells were found in a vaginal fragment after 1 month of the neovaginoplasty. Typical vaginal epithelium was also observed and the reaction for identification of glycogen (PAS) was positive 9 months after surgery in all cases. Conclusions: The oxidized cellulose membrane proved to be a suitable material to use as coating of the neovagina for the correction of congenital defects such as vaginal agenesis. It is possible to obtain a typical vaginal epithelium after the use of this absorbable adhesion barrier. (J GYNECOL SURG 29:169)