Assay of major and minor constituents of opium samples and studies of their origin
1979; Elsevier BV; Volume: 14; Issue: 3 Linguagem: Inglês
10.1016/0379-0738(79)90138-5
ISSN1872-6283
AutoresK. Narayanaswami, H.C. Golani, Rajiv Dua,
Tópico(s)Chemical synthesis and alkaloids
ResumoSamples of opium from different countries as well as from various regions of India were studied for their morphine and codeine content by gas-liquid chromatography (GLC) as their silyl ethers in a single step. Non-phenolic alkaloids (thebaine, papaverine and narcotine) were extracted with dichloromethane for GLC after conversion of the meconic acid, morphine and codeine in opium into insoluble salts with lime water. The data on alkaloidal constituents have been utilised in a determination of the origin of seized opium samples in this preliminary study.
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