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Evaluation of air-displacement plethysmography for body composition assessment in preterm infants

2012; Springer Nature; Volume: 72; Issue: 3 Linguagem: Inglês

10.1038/pr.2012.75

1530-0447

Paola Roggero, Maria Lorella Giannì, Orsola Amato, Pasqua Piemontese, Daniela Morniroli, William W. Wong, Fabio Mosca,

Infant Development and Preterm Care

Adiposity may contribute to the future risk of disease. The aim of this study was to evaluate the accuracy and reliability of an air-displacement plethysmography (ADP) system to estimate percentage fat mass (%FM) in preterm infants and to evaluate interdevice reliability in infants. A total of 70 preterm and 9 full-term infants were assessed. The accuracy of ADP measurements was assessed by determining reference %FM values using H218O dilution measurement. Mean %FM by ADP was 5.67 ± 1.84 and mean %FM by H218O dilution was 5.99 ± 2.56. Regression analysis showed that %FM by ADP was associated with %FM by H218O dilution (R2 = 0.63, SE of estimate (SEE) = 1.65, P = 0.006). Bland–Altman analysis showed no bias (r = −0.48, P = 0.16) and 95% limits of agreement were −3.40 to 2.76 %FM. There was no difference in mean interdevice reliability %FM values (8.97 vs. 8.55 %FM) between ADP 1 and 2. Regression analysis indicated a low SEE (1.14% FM) and high R2 (0.91); 95% limits of agreement were −1.87 to 2.71 %FM. The regression line did not differ significantly from the line of identity. ADP is a noninvasive, reliable, and accurate technique to measure preterm infants’ body composition in both research and clinical settings.