Portal de Periódicos da CAPES

Thyroid cancer in Ukraine after the Chernobyl accident (in the framework of the Ukraine–US Thyroid Project)

2012; IOP Publishing; Volume: 32; Issue: 1 Linguagem: Inglês

10.1088/0952-4746/32/1/n65

1361-6498

М.D. Тronko, Kiyóhiko Mabuchi, Bogdanova Ti, Maureen Hatch, Likhtarev Ia, André Bouville, Valeriy Oliynik, Robert J. McConnell, Victor Shpak, Lydia B. Zablotska, Valeriy Tereshchenko, Alina V. Brenner, Galyna Zamotayeva,

Radioactive contamination and transfer

As a result of the accident at the Chernobyl Nuclear Power Plant, millions of residents of Belarus, Russia, and Ukraine were exposed to large doses of radioactive iodine isotopes, mainly I-131. The purpose of the Ukraine-American (UkrAm) and Belarus-American (BelAm) projects are to quantify the risks of thyroid cancer in the framework of a classical cohort study, comprising subjects who were aged under 18 years at the time of the accident, had direct measurements of thyroid I-131 radioactivity taken within two months after the accident, and were residents of three heavily contaminated northern regions of Ukraine (Zhitomir, Kiev, and Chernigov regions). Four two-year screening examination cycles were implemented from 1998 until 2007 to study the risks associated with thyroid cancer due to the iodine exposure caused during the Chernobyl accident. A standardised procedure of clinical examinations included: thyroid palpation, ultrasound examination, blood collection followed by a determination of thyroid hormone levels, urinary iodine content test, and fine-needle aspiration if required. Among the 110 cases of thyroid cancer diagnosed in UkrAm as the result of four screening examinations, 104 cases (94.5%) of papillary carcinomas, five cases (4.6%) of follicular carcinomas, and one case (0.9%) of medullary carcinoma were diagnosed.