Heavy-Particle Therapy in Acromegaly and Cushing Disease
1976; American Medical Association; Volume: 235; Issue: 21 Linguagem: Inglês
10.1001/jama.1976.03260470025019
ISSN1538-3598
Autores Tópico(s)Glioma Diagnosis and Treatment
ResumoA total of 349 patients with pituitary tumors, including acromegaly, Cushing disease, Nelson syndrome, prolactin-secreting adenoma, and chromophobe adenoma, have been treated with heavy-particle radiation during the past 17 years. The incidence of side effects has been low. Only 30 patients (8.6%) have died, most of preexisting cardiovascular complications. Heavy-particle therapy provides a form of treatment with no mortality and extremely low morbidity, and its use in treating pituitary disorders has resulted in dramatic improvement in the signs and symptoms of patients with acromegaly and Cushing disease. ( JAMA 235:2307-2310, 1976)
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