Produção Nacional
Revisado por pares
Urinary dysfunction with detrusor hyperactivity in women with Parkinson's disease cannot be blamed as a factor of worsening motor performance
2013; Thieme Medical Publishers (Germany); Volume: 71; Issue: 9A Linguagem: Inglês
10.1590/0004-282x20130101
ISSN1678-4227
AutoresRaimundo Nonato Campos-Sousa, Elizabeth Maria Aparecida Barasnevicius Quagliato, Kelson James Almeida, Inácio Augusto Dias de Castro, Viriato Campelo,
Tópico(s)Restless Legs Syndrome Research
ResumoIntroduction Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature. Methods A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated. Results Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups. Conclusion Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.
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