Exome sequencing and the genetic basis of complex traits
2012; Nature Portfolio; Volume: 44; Issue: 6 Linguagem: Inglês
10.1038/ng.2303
ISSN1546-1718
AutoresAdam Kieżun, Kiran Garimella, Ron Do, Nathan O. Stitziel, Benjamin M. Neale, Paul J. McLaren, Namrata Gupta, Pamela Sklar, Patrick F. Sullivan, Jennifer L. Moran, Christina M. Hultman, Paul Lichtenstein, Patrik K. E. Magnusson, Thomas Lehner, Yin Yao Shugart, Alkes L. Price, Paul I. W. de Bakker, Shaun Purcell, Shamil Sunyaev,
Tópico(s)Epigenetics and DNA Methylation
ResumoShamil Sunyaev and colleagues present exome sequencing methods and their applications in studies to identify the genetic basis of human complex traits. They include analyses of the whole-exome sequences of 438 individuals from across several studies.
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