Total Synthesis of the Ethyl Ester of the Major Urinary Metabolite of Prostaglandin E 2
2002; American Chemical Society; Volume: 67; Issue: 5 Linguagem: Inglês
10.1021/jo011017i
ISSN1520-6904
AutoresDouglass F. Taber, Dawei Teng,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoThe preparation of the ethyl ester of the major urinary metabolite of prostaglandin E(2) 3 is described. The key step is the kinetic opening of the TBS-protected bicyclic ketone 7 with thiophenol.
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