Artigo Revisado por pares

Total Synthesis of the Ethyl Ester of the Major Urinary Metabolite of Prostaglandin E 2

2002; American Chemical Society; Volume: 67; Issue: 5 Linguagem: Inglês

10.1021/jo011017i

ISSN

1520-6904

Autores

Douglass F. Taber, Dawei Teng,

Tópico(s)

Asymmetric Synthesis and Catalysis

Resumo

The preparation of the ethyl ester of the major urinary metabolite of prostaglandin E(2) 3 is described. The key step is the kinetic opening of the TBS-protected bicyclic ketone 7 with thiophenol.

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