Portal de Periódicos da CAPES

Control of VSG gene expression sites in Trypanosoma brucei

1998; Elsevier BV; Volume: 91; Issue: 1 Linguagem: Inglês

10.1016/s0166-6851(97)00184-9

1872-9428

Piet Borst,

Biochemical and Molecular Research

Antigenic variation in African trypanosomes continues to be one of the most elaborate and intriguing strategies ever devised by a protozoan parasite to avoid complete destruction by the immune defense of its mammalian host. Here we review some of the recent advances in our understanding of this strategy, concentrating on (unpublished) work from our laboratory.