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Thymosin Induced Changes in the Cell Cycle of Lymphocytes from Aging Neonatally Thymectomized Rats

1976; Marcel Dekker; Volume: 5; Issue: 7-8 Linguagem: Inglês

10.3109/08820137609033877

0090-0877

Marek Dąbrowski, Allan L. Goldstein,

Spaceflight effects on biology

The potential role of the endocrine thymus on the cell cycle of lymphocytes from aging neonatally thymectomized rats (LAT cells) was investigated using thymosin fraction 5. Thymosin rendered LAT cells similar to normal lymphocytes with regard to reconstituting the median S+G2 phase of the LAT cell. This is the first study to demonstrate an effect of thymosin on the cell cycle of lymphocyte populations.