Clathrin uncoating: Auxilin comes to life
2001; Elsevier BV; Volume: 11; Issue: 2 Linguagem: Inglês
10.1016/s0960-9822(01)00010-0
ISSN1879-0445
Autores Tópico(s)Endoplasmic Reticulum Stress and Disease
ResumoThe DnaJ protein auxilin has been extensively studied in vitro as a cofactor for uncoating clathrin-coated vesicles by the chaperone Hsc70. Recent studies provide the first evidence that auxilin plays this role in vivo, and work on a new mammalian auxilin suggests the protein may have more complex cellular functions.
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