Understanding the role of the CD40–CD40L interaction in resistance to parasitic infections
2003; Wiley; Volume: 25; Issue: 4 Linguagem: Inglês
10.1046/j.1365-3024.2003.00624.x
ISSN1365-3024
AutoresEmma H. Wilson, Christopher A. Hunter,
Tópico(s)T-cell and B-cell Immunology
ResumoParasite ImmunologyVolume 25, Issue 4 p. 179-183 Understanding the role of the CD40–CD40L interaction in resistance to parasitic infections Emma H. Wilson, Emma H. Wilson Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USASearch for more papers by this authorChristopher A. Hunter, Corresponding Author Christopher A. Hunter Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USACorrespondence: Christopher A. Hunter, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USA (e-mail: [email protected]).Search for more papers by this author Emma H. Wilson, Emma H. Wilson Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USASearch for more papers by this authorChristopher A. Hunter, Corresponding Author Christopher A. Hunter Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USACorrespondence: Christopher A. Hunter, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USA (e-mail: [email protected]).Search for more papers by this author First published: 27 August 2003 https://doi.org/10.1046/j.1365-3024.2003.00624.xCitations: 6Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Arpin C, Dechanet J, Van Kooten C et al. Generation of memory B cells and plasma cells in vitro. Science 1995; 268: 720–722. 2 Notarangelo LD, Duse M & Ugazio AG. Immunodeficiency with hyper-IgM (HIGM). Immunodefic Rev 1992; 3: 101. 3 Allen RC, Armitage RJ, Conley ME et al. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 1993; 259: 990–993. 4 Aruffo A, Farrington M, Hollenbaugh D et al. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell 1993; 72: 291. 5 Callard RE, Smith SH, Herbert J et al. CD40 ligand (CD40L) expression and B cell function in agammaglobulinemia with normal or elevated levels of IgM (HIM). J Immunol 1994; 153: 3295. 6 DiSanto JP, Bonnefoy JY, Gauchat JF, Fischer A & De Saint Basile G. CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM. Nature 1993; 361: 541. 7 Fuleihan R, Ramesh N, Loh R et al. Defective expression of the CD40 ligand in X-linked immunodeficiency with normal or elevated IgM (HIGMX-1). Proc Nat Acad Sci USA 1993; 90: 2170. 8 Korthauer U, Garf D, Mages HW et al. Defective expression of T cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 1993; 361: 539. 9 Levy J, Espanol-Boren T, Thomas C et al. Clinical spectrum of X-linked hyper-IgM syndrome. J Pediatr 1997; 131: 47–54. 10 Tsuge I, Matsuoka H, Nakagawa A et al. Necrotizing toxoplasmic encephalitis in a child with the X-linked hyper-IgM syndrome. Eur J Pediatr 1998; 157: 735–737. 11 Yap G, Pesin M & Sher A. IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen Toxoplasma gondii. J Immunol 2000; 165: 628–631. 12 Subauste CS, Wessendarp M, Sorensen RU & Leiva LE. CD40–CD40 ligand interaction is central to cell-mediated immunity against Toxoplasma gondii: patients with hyper IgM syndrome have a defective type-1 immune response which can be restored by soluble CD40L trimer. J Immunol 1999; 162: 6690–6700. 13 Subauste CS & Wessendarp M. Human dendritic cells discriminate between viable and killed Toxoplasma gondii: dendritic cell activation after activation with viable parasites results in CD28 and CD40 signaling that controls IL-12-dependent and independent T cell production of IFN-g. J Immunol 2000; 165: 1498–1505. 14 Zhou P & Seder RA. CD40 ligand is not essential for induction of type-1 cytokine responses or protective immunity after primary or secondary infection with Histoplasma capsulatum. J Exp Med 1998; 187: 1315–1324. 15 Campos-Neto A, Ovendale P, Bement T et al. Cutting Edge: CD40 ligand is not essential for the development of cell-mediated immunity and resistance to Mycobacterium tuberculosis. J Immunol 1998; 160: 2037–2041. 16 Reichmann G, Walker W, Villegas EN et al. The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis. Infect Immun 2000; 68: 1312–1318. 17 Becher B, Blain M & Antel JP. CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS. J Neuroimmunol 2000; 102: 44–50. 18 Becher B, Durell BG, Miga AV, Hickey WF & Noelle RJ. The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system. J Exp Med 2001; 193: 967–974. 19 D'Aversa TG, Weidenheim KM & Berman JW. CD40–CD40L interactions induce chemokine expression by human microglia. Am J Path 2002; 160: 559–567. 20 Tan J, Town T, Mori T et al. CD40 is expressed and functional on neuronal cells. EMBO J 2002; 21: 643–652. 21 Jana M, Liu X, Koka S, Ghosh S, Petro TM & Pahan K. Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells. J Biol Chem 2001; 276: 44527–44533. 22 De Goer de Herve MG, Delfraissy JF & Taoufik Y. Following direct CD40 activation, human primary microglial cells produce IL-12 p40 but not bioactive IL-12 p70. Cytokine 2001; 14: 88–96. 23 Fischer H, Bonifas U & Reichmann G. Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii. J Immunol 2000; 164: 4826–4834. 24 Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavechia A & Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 1996; 184: 747–752. 25 Cosyns M, Tsirkin S, Jones M, Flavell R, Kikutani H & Hayward AR. Requirement for CD40–CD40 ligand interaction for elimination of Cryptosporidium parvum from mice. Infect Immun 1998; 66: 603–607. 26 Hayward AR, Levy J, Facchetti F et al. Cholangiopathy and tumors of the pancreas, liver, and biliary tree in boys with X-linked immunodeficiency with hyper-IgM. J Immunol 1997; 158: 977–983. 27 Hayward AR, Cosyns M, Jones M & Ponnuraj EM. Marrow-derived CD40-positive cells are required for mice to clear Cryptosporidium parvum infection. Infect Immun 2001; 69: 1630–1634. 28 Martin JC, Sancho T, Sierra FJ et al. Visceral leishmaniasis in a patient with hyper-IgM hypogammaglobulinemia. Clin Infect Dis 1996; 23: 1188–1189. 29 Campbell KA, Ovendale PJ, Kennedy MK, Fanslow WC, Reed SG & Maliszewski CR. CD40 ligand is required for protective cell-mediated immunity to Leishmania major. Immunity 1996; 4: 283–289. 30 Kamanaka M, Yu, P, Yasui T, Yoshida K et al. Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity. Immunity 1996; 4: 275–281. 31 Soong L, Jian-Chao X, Grewal IS et al. Disruption of CD40–CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity 1996; 4: 263–273. 32 Ferlin WG, Von Der Weid T, Cottrez F, Ferrick DA, Coffman & Howard MC. The induction of a protective response in Leishmania major-infected BALB/c mice with anti-CD40 mAb. Eur J Immunol 1998; 28: 525–531. 33 Marovich MA, McDowell MA, Thomas EK & Nutman TB. IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process. J Immunol 2000; 164: 5858–5865. 34 Speirs K, Caamano J, Goldschmidt MH, Hunter CA & Scott P. NF-kB2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell differentiation. J Immunol 2002; 168: 4406–4413. 35 Padigel UM, Perrin PJ & Farrell JP. The development of a Th1-type response and resistance to Leishmania major infection in the absence of CD40–CD40L costimulation. J Immunol 2000; 167: 5874–5879. 36 Padigel UM & Farrell JP. CD40–CD40 ligand costimulation is not required for initiation and maintenance of a Th1-type response to Leishmania major infection. Infect Immun 2003; 71: 1389–1395. 37 Lu P, Urban JF, Zhou XD et al. CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production. J Immunol 1996; 156: 3327–3333. 38 MacDonald AS, Straw AD, Dalton NM & Pearce EJ. Cutting edge: Th2 response induction by dendritic cells: a role for CD40. J Immunol 2002; 168: 537–540. 39 Martin DL, King CL, Pearlman E, Strine E & Heinzel FP. IFN-γ is necessary but not sufficient for anti-CD40 antibody-mediated inhibition of the Th2 response to Schistosoma mansoni eggs. J Immunol 2000; 164: 779–785. 40 MacDonald AS, Patton EA, La Flamme AC et al. Impaired Th2 development and increased mortality during Schistosoma mansoni infection in the absence of CD40/CD154 interaction. J Immunol 2002; 168: 4643–4649. 41 Straw AD, MacDonald AS, Denkers EY & Pearce EJ. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. J Immunol 2003; 170: 727–734. 42 Imai S, Tezuka H, Furuhashi Y, Muto R & Fujita K. A factor of inducing IgE from a filarial parasite is an agonist of human CD40. J Biol Chem 2000; 276: 46118–46124. 43 Tezuka H, Imai S, Tsukidate S & Fujita K. A Dirofilaria immitis polyprotein up-regulates nitric oxide production. Infect Immun 2002; 70: 5283–5286. 44 Van Overtvelt L, Vandereyde N, Verhasselt V et al. Trypanasoma cruzi infects human dendritic cells and prevents their maturation: Inhibition of cytokines, HLA-DR, and costimulatory molecules. Infect Immunol 1999; 67: 4033–4040. 45 Moutaftsi M, Mehl AM, Borysiewicz LK & Tabi Z. Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells. Blood, 2002; 99: 2913– 2921. 46 Uronen H & Callard RE. Absence of CD40–CD40 ligand interactions in X-linked hyper-IgM syndrome does not affect differentiation of T helper cell subsets. Clin Exp Immunol 2000; 121: 346–352. 47 Bourgeois C, Rocha B & Tanchot C. A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory. Science 2002; 297: 2060–2063. Citing Literature Volume25, Issue4April 2003Pages 179-183 ReferencesRelatedInformation
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