INTRAVENOUS INFUSION OF SALBUTAMOL IN THE MANAGEMENT OF PREMATURE LABOUR
1973; Wiley; Volume: 80; Issue: 1 Linguagem: Inglês
10.1111/j.1471-0528.1973.tb02126.x
ISSN1471-0528
Autores Tópico(s)Cardiovascular Issues in Pregnancy
ResumoSummary Salbutamol, a ß‐adrenergic stimulant, was administered to 88 women in premature labour in an attempt to delay delivery by 24 hours while corticosteroid was administered to prevent respiratory distress syndrome in the newborn. Treatment by continuous intravenous infusion of salbutamol varied in duration from 6 to 72 hours and the dose ranged from 1.8–43 μg. per minute. Delivery was postponed for more than 24 hours in 85 per cent of patients. The presence of ruptured membranes did not influence the outcome of treatment but dilatation of the cervix beyond 4 cm. was associated with successful treatment in only 58 per cent. No serious side effects were noted but tachycardia up to 140 per minute occurred frequently. It is concluded that salbutamol is a safe, well tolerated and effective uterine relaxant.
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