Hyperparathyroidism and Peptic Ulcer Disease
1968; American Medical Association; Volume: 96; Issue: 1 Linguagem: Inglês
10.1001/archsurg.1968.01330190116026
ISSN1538-3644
Autores Tópico(s)Autoimmune and Inflammatory Disorders
ResumoTHE FIRST hyperfunctioning parathyroid carcinoma with metastases was reported in 1939 by Meyer. 1 The association of peptic ulcer and hyperparathyroidism was emphasized by Rogers 2 in 1946 and by Rogers et al in 1947. 3 In 1950, Haynes reviewed all cases of hyperparathyroidism seen at the Mayo Clinic and found that 24% of the patients with proved hyperparathyroidism had at the time of examination, or in the past, objective evidence of peptic ulcer or surgical procedures presumably for ulcers. The majority of the ulcers were duodenal. An additional 15% to 20% of the patients had ulcerlike symptoms. 4 The first question that must be investigated in a discussion of the relationship between hyperparathyroidism and peptic ulcer is whether the concurrent incidence of these two diseases is higher than the corresponding incidence of peptic ulcer in the general population. Unfortunately, this is not feasible since investigations to determine the incidence
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