Portal de Periódicos da CAPES

Accidental intrathecal administration of vincristine

1978; Alan R. Liss, Inc.; Volume: 5; Issue: 1 Linguagem: Inglês

10.1002/mpo.2950050113

1096-911X

Dell A. Shepherd, C. Philip Steuber, Kenneth A. Starling, Donald J. Fernbach,

Spinal Hematomas and Complications

Abstract Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, discuss possible means of therapeutic intervention, and serve as a reminder that preventive measures are mandatory to avoid such accidents in the future.