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Diurnal Variation of Intraocular Pressure in the Normal Eye

1963; American Medical Association; Volume: 69; Issue: 6 Linguagem: Inglês

10.1001/archopht.1963.00960040758013

1538-3601

Guillermo de Venecia, Matthew D. Davis,

Cerebral Venous Sinus Thrombosis

Diurnal variation of intraocular pressure has been the subject of considerable interest and speculation since Maslenikow 1 first called attention to it in 1904. Many authors writing on this subject have suggested that exaggeration of the normal diurnal pressure fluctuation is characteristic of early chronic open-angle glaucoma. As recently pointed out by Leydhecker, 2 however, there seems to be little agreement as to the upper limit of "normal" diurnal variation, the value cited by various authors ranging between 2 and 10 mm Hg (Table 1). Moreover, only a few authors have presented convincing evidence to substantiate their opinions. The most pertinent study is that of Drance, 3 who measured the intraocular pressure in 404 eyes without glaucoma in a general hospital, recording tensions with the Schiøtz tonometer at 6, 9, and 11:30 am, and 2, 5, and 10 pm during the day. Diurnal variation in these patients ranged from 0