Portal de Periódicos da CAPES

Effect of the exocrine pancreatic secretions on iron absorption.

1967; BMJ; Volume: 8; Issue: 6 Linguagem: Inglês

10.1136/gut.8.6.556

1468-3288

Hymie Kavin, R. W. Charlton, P Jacobs, R Green, J. D. Torrance, T. H. Bothwell,

Pancreatitis Pathology and Treatment

EDITORIAL COMMENT The influence of pancreatic extract on iron salts and their absorption has been investigated in vitro, in experimental animals, and in patients with pancreatic insufficiency.It is suggested that the binding of iron by pancreatic extract is non-specific adsorption and that pancreatic exocrine secretions play little or no part in the physiological control of iron absorption.The role of the exocrine secretions of the pancreas in the absorption of iron has been the subject of extensive investigation.There is a considerable body of evidence indicating that deficiency of the pancreatic secretions leads to excessive absorption of iron, and consists of observations both in experimental animals and in human subjects.The animal evidence includes the increase in carcass iron observed after pancreatectomy (Taylor, Stiven, and Reid, 1931), after ligation of the pancreatic duct (Taylor, Stiven, and Reid, 1935; Gillman,