General access to polyhydroxylated nortropane derivatives through hetero Diels–Alder cycloadditions. Part 3: Synthesis of natural (+)-calystegine B2
1999; Elsevier BV; Volume: 10; Issue: 11 Linguagem: Inglês
10.1016/s0957-4166(99)00204-9
ISSN1362-511X
AutoresThomas Faitg, Josette Soulié, Jean‐Yves Lallemand, Louis Ricard,
Tópico(s)Microbial Natural Products and Biosynthesis
ResumoCycloaddition of chiral nitroso derivatives with cyclohepta-1,3-diene gave one single stereoisomer with an excellent selectivity. The structures including absolute configurations have been assigned by spectroscopy and X-ray crystallography. These studies have been applied to the total synthesis of the naturally occurring calystegine B2.
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