Type-2 diabetes and cognitive function in a non-demented population
2009; Wiley; Volume: 100; Issue: 2 Linguagem: Inglês
10.1111/j.1600-0404.1999.tb01045.x
ISSN1600-0404
AutoresMatti Vanhanen, Johanna Kuusisto, Keijo Koivisto, Leena Mykkänen, E.-L. Helkala, Tuomo Hänninen, Paavo Riekkinen, Hilkka Soininen, Markku Laakso,
Tópico(s)Parkinson's Disease Mechanisms and Treatments
ResumoActa Neurologica ScandinavicaVolume 100, Issue 2 p. 97-101 Type-2 diabetes and cognitive function in a non-demented population M. Vanhanen, Corresponding Author M. Vanhanen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandMatti Vanhanen, Department of Neurology, Kuopio University Hospital, POB 1627, FIN-70211 Kuopio, FinlandSearch for more papers by this authorJ. Kuusisto, J. Kuusisto Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorK. Koivisto, K. Koivisto Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorL. Mykkänen, L. Mykkänen Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorE-L. Helkala, E-L. Helkala Public Health and General Practice University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorT. Hänninen, T. Hänninen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorP. Riekkinen, P. Riekkinen A.I. Virtanen Institute of Kuopio University and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorH. Soininen, H. Soininen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorM. Laakso, M. Laakso Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this author M. Vanhanen, Corresponding Author M. Vanhanen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandMatti Vanhanen, Department of Neurology, Kuopio University Hospital, POB 1627, FIN-70211 Kuopio, FinlandSearch for more papers by this authorJ. Kuusisto, J. Kuusisto Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorK. Koivisto, K. Koivisto Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorL. Mykkänen, L. Mykkänen Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorE-L. Helkala, E-L. Helkala Public Health and General Practice University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorT. Hänninen, T. Hänninen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorP. Riekkinen, P. Riekkinen A.I. Virtanen Institute of Kuopio University and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorH. Soininen, H. Soininen Departments of Neurology University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this authorM. Laakso, M. Laakso Medicine and University Hospital of Kuopio, POB 1627, FIN-70211, Kuopio, FinlandSearch for more papers by this author First published: 29 January 2009 https://doi.org/10.1111/j.1600-0404.1999.tb01045.xCitations: 38AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Objectives - To study if type-2 (non-insulin-dependent) diabetes mellitus (NIDDM) is associated with cognitive dysfunction independently of clinically diagnosed dementia in an elderly population. Material and methods - Cognitive function was investigated with a brief neuropsychological test battery in a non-demented elderly population consisting of 183 NIDDM (World Health Organization, 1985) patients and 732 non-diabetic subjects. Results - Patients with NIDDM were impaired in the Trail-Making Test parts A and C, which may be a reflection of mildly affected frontal lobe/executive functions. Women with NIDDM performed better than non-diabetic subjects in the Mini-Mental State Examination. Conclusions - We conclude that NIDDM per se is not associated with impaired memory in the elderly, and the minor defects observed in tests of frontal lobe/executive functions are unlikely to affect daily living. In the non-demented population aged 69-78 years, NIDDM does not carry a significant risk of cognitive dysfunction, when compared to the non-diabetic subjects. Citing Literature Volume100, Issue2August 1999Pages 97-101 RelatedInformation
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