Combining BCR-ABL1 transcript levels at 3 and 6 months in chronic myeloid leukemia: implications for early intervention strategies
2013; Elsevier BV; Volume: 121; Issue: 14 Linguagem: Inglês
10.1182/blood-2012-11-466037
ISSN1528-0020
AutoresPratap Neelakantan, Gareth Gerrard, Claire Lucas, Dragana Milojković, Philippa C. May, Lihui Wang, Christos Paliompeis, Marco Bua, Alistair Reid, Katayoun Rezvani, Stephen J. O’Brien, Richard E. Clark, John M. Goldman, David Marin,
Tópico(s)Acute Lymphoblastic Leukemia research
ResumoKey Points Response to TKIs can be accurately established by measuring the 3-month transcript level. An additional measurement of the transcript level at 6 months adds very little useful clinical information to the 3-month result.
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