Voltar
Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

EFFECTS OF INTENSE AND SUBMAXIMAL TRAINING PROTOCOLS UPON LIVER AND MUSCLE LONG CHAIN FATTY ACID OXIDATION CAPACITY.

1998; Lippincott Williams & Wilkins; Volume: 30; Issue: Supplement Linguagem: Inglês

10.1097/00005768-199805001-01202

ISSN

1530-0315

Autores

Mar Belmonte, H. F. Bacurau, L FBP Costa Rosa, Marília Seelaender,

Tópico(s)

Muscle metabolism and nutrition

Resumo

1202 Endurance training enhances the capacity of skeletal muscle to oxidise fatty acids. Not much is known, however, in relation to liver lipid oxidative capacity under the influence of physical exertion. Long-chain fatty acids do not freely permeate the mitochondrial membranes, depending on the activity of an enzymatic complex, which includes carnitine palmitoyltransferase I (CPT I), carnitine acyl-carnitine translocase and carnitine palmitoyltransferase II(CPT II) to reach the mitochondrial matrix. CPT I is currently accepted as the main step of regulation of fatty acid oxidation. Recently, however, our own group and others have demonstrated an important participation of CPT II in the control of fatty acid transport in the mitochondria. We have presently measured the activity of CPT I and II in the soleus muscle and liver of rats submitted to submaximal exercise training (rats ran on a treadmill for 7 weeks, 5 days/week until able to run 18m/min in 1h- 70% VO2 max-TC) and in the liver of rats after an intense training protocol (7 weeks, 5 days/week, until able to run 30 m/min- 85% VO2 max-TI). Table 1, Table 2Table 1: CPT I and II maximal activities in the liver and soleus muscle of rats submitted to a moderate intensity training protocol. (nmols/min/mg proteina)Table 2: CPT I and CPT II activities after intense exercise training in the liver of ratsThese results indicate that the moderate intensity training protocol augmented the maximal activities of CPT I and CPT II in the soleus muscle, as it would be expected, and that both training protocols, TC and TI did not altered the maximal activity of the enzymatic complex in the liver.

Referência(s)