(S)-5-Nitro-2-pentanol durch Reduktion mit Bäckerhefe

1989; Wiley; Volume: 1989; Issue: 9 Linguagem: Inglês

10.1002/jlac.198919890247

ISSN

0170-2041

Autores

Thomas Hafner, Hans‐Ulrich Reißig,

Tópico(s)

Chemical synthesis and alkaloids

Resumo

( S )‐5‐Nitro‐2‐pentanol by Reduction with Baker′s Yeast The title compound 2 is prepared with 96% enantiomeric excess in reasonable yield employing baker′s yeast under aerobic conditions. The absolute configuration has been established by conversion of 2 into ( S )‐4,5‐dihydro‐5‐inethyl‐2(3/)‐furanone ( 4 ).

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