Absolute stereochemistry of cicutoxin and related toxic polyacetylenic alcohols from Cicuta virosa
1999; Elsevier BV; Volume: 55; Issue: 41 Linguagem: Inglês
10.1016/s0040-4020(99)00706-1
ISSN1464-5416
AutoresTomihisa Ohta, Koji Uwai, Rikako Kikuchi, Shigeo Nozoe, Yoshiteru Oshima, Kenrou Sasaki, Fumihiko Yoshizaki,
Tópico(s)Mycotoxins in Agriculture and Food
ResumoThe absolute stereostructures of cicutoxin (1) and related toxic polyacetylenic alcohols, isocicutoxin (2), and virols A (3) and C (4), from Cicuta virosa were determined on the basis of spectroscopic analysis. The CD exciton chirality method was successfully applied to 4-methoxybenzoates of diyne-conjugated polyenyl alcohol systems. Fatal doses of these compounds on mice are also reported.
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