Flow Cytometric Analysis of the Maldescended Testis
2009; Wiley; Volume: 17; Issue: 4 Linguagem: Inglês
10.1111/j.1439-0272.1985.tb01027.x
ISSN1439-0272
AutoresU. Hacker-Klom, G. Kleinhans, W. Göhde,
Tópico(s)Sperm and Testicular Function
ResumoFlow cytometric measurements of the cellular DNA contents of 16 testicular biopsies of 15 patients with maldescended testes were performed. 2 patients were children. 11 patients of pubescent or adult age had no haploid germ cells in the tissue of their maldescended testis. One patient with a testis mobilis had about a normal percentage of haploid germ cells. In one patient a malignant tumor was detected unexpectedly by an aneuploid stem line at 2.2 c. Flow cytometric analysis of human testicular biopsy material is an easy and a fast way to quantify the function of spermatogenesis and detect malignancies.
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