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A “Short” Feedback Loop in the Control of ACTH Secretion

1965; Oxford University Press; Volume: 77; Issue: 2 Linguagem: Inglês

10.1210/endo-77-2-392

1945-7170

Marcella Motta, GIUSEPPE MANGILI, Luciano Martini,

Stress Responses and Cortisol

Permanent ACTH implants (USP Reference Standard and synthetic β1-24- corticotrophin) into the median eminence significantly depress blood corticosterone levels in the rat, suggesting that a "short" feedback loop might link synthesis and/or release of ACTH to pre-existing levels of the hormone. (Endocrinology77: 392, 1965)