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Antibacterial characteristics of CaCO3–MgO composites

2009; Elsevier BV; Volume: 173; Issue: 1-3 Linguagem: Inglês

10.1016/j.mseb.2009.12.007

1873-4944

Osamu Yamamoto, Toshiaki Ohira, Kelly Alvarez, Masayuki Fukuda,

Nanoparticles: synthesis and applications

Dentifrices, such as tooth-paste, are pastes containing insoluble abrasives that aid in the removal of plaque from the teeth and help to polish them. Composite powders contributing to oral hygiene application, i.e., nano-scale MgO crystallite dispersed in CaCO3 grain, were fabricated by the thermal decomposition of dolomite. The composite obtained by heating at 800 °C consisted of CaCO3 grains including 20 nm MgO fine crystallite, being the purpose powder in this study. The antibacterial activity of these powders related to gram-positive and gram-negative bacteria was evaluated in vitro. The thermal decomposition above 800 °C resulted in the mixture of CaO and MgO. Antibacterial activity of the composite enhanced with increasing powder concentration. Though antibacterial action toward Staphylococcus aureus was greater than towards Escherichia coli, the death rate constant was identical in both bacteria. It can be concluded that the obtained composite possesses two functions able to improve the oral hygiene: as a tooth abrasive and as an antibacterial agent.