Heterogeneous Henry reaction of aldehydes: Diastereoselective synthesis of nitroalcohol derivatives over Mg-Al hydrotalcites
1999; Elsevier BV; Volume: 55; Issue: 30 Linguagem: Inglês
10.1016/s0040-4020(99)00494-9
ISSN1464-5416
AutoresVivek J. Bulbule, V. H. DESHPANDE, Subramani Velu, Arumugam Sudalai, S. Sivasankar, V.T. Sathe,
Tópico(s)Inorganic Chemistry and Materials
ResumoMg-Al Hydrotalcite (HT) has been found to catalyze the reaction between aldehydes and nitroalkanes very efficiently affording threo nitroalkanols in a highly diastereoselective manner. The ratios of threoerythro isomers are determined from their respective 13C-NMR spectra. A mechanism based on the transition state model for the predominant formation of threo-isomers is also described.
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