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Erythema elevatum diutinum. Presentation of a case and evaluation of laboratory and immunological status

1967; American Medical Association; Volume: 96; Issue: 3 Linguagem: Inglês

10.1001/archderm.96.3.235

1538-3652

John Paul Mraz,

Hidradenitis Suppurativa and Treatments

Erythema elevatum diutinum (EED) is a chronic cutaneous disease characterized by nodules and plaques in an acral and symmetrical location. Histologically, the earliest findings are a vasculitis in the dermis associated with an inflammatory-cell infiltrate and a tinctorial change in the vessel wall and adjacent perivascular fibers. The histologic findings are thought to be highly characteristic. Extracellular cholesterosis (EC) most likely represents a variant in which lipids are secondarily deposited between the collagen bundles. The earlier division of EED into the Hutchinson and Bury types is no longer thought to be warranted. A patient is presented with clinical and histological features of EED; an elevation of several amino acids in the urine with essentially normal plasma levels was revealed. Elevations of IgG and IgA, and a mild elevation in leukocyte alkaline phosphatase were present.