Artigo Acesso aberto Revisado por pares

Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection, Italy, August 2013

2013; European Centre for Disease Prevention and Control; Volume: 18; Issue: 38 Linguagem: Inglês

10.2807/1560-7917.es2013.18.38.20591

ISSN

1560-7917

Autores

Luisa Barzon, Monia Pacenti, Elisa Franchin, Enrico Lavezzo, Giulia Masi, Laura Squarzon, Silvana Pagni, Stefano Toppo, Francesca Russo, Margherita Cattai, Riccardo Cusinato, Giorgio Palù,

Tópico(s)

Insect symbiosis and bacterial influences

Resumo

A human outbreak of West Nile virus (WNV) infection caused by WNV lineage 2 is ongoing in northern Italy. Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain. In addition, WNV lineage 1 Livenza, responsible for a large outbreak in north-eastern Italy in 2012, was fully sequenced from a blood donor during this 2013 outbreak.

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