A Practical, Highly Stereoselective Synthesis of the Trisaccharide Repeating Unit of a Streptococcus pneumoniae Polysaccharide
1992; Oxford University Press; Volume: 21; Issue: 5 Linguagem: Inglês
10.1246/cl.1992.707
ISSN1348-0715
AutoresEisuke Kaji, Frieder W. Lichtenthaler, Yumiko Osa, Keiko Takahashi, Eiko Matsui, Shonosuke Zen,
Tópico(s)Pneumonia and Respiratory Infections
ResumoAbstract A highly stereoselective method has been developed for the synthesis of the trisaccharide component of the capsular polysaccharide of Streptococcus pneumoniae type 19F. The key intermediate, 2-benzoyloxyiminoglycosyl bromide was successfully utilized for the construction of the N-acetyl-β-D-mannosamine unit of the trisaccharide.
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