Artigo Acesso aberto Revisado por pares

Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood Stabilities

1999; American Chemical Society; Volume: 42; Issue: 16 Linguagem: Inglês

10.1021/jm9902279

ISSN

1520-4804

Autores

David Bom, Dennis P. Curran, Ashok J. Chavan, Stefan Kruszewski, Stephen G. Zimmer, Kimberly A. Fraley, Thomas G. Burke,

Tópico(s)

DNA and Nucleic Acid Chemistry

Resumo

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTNovel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood StabilitiesDavid Bom, Dennis P. Curran, Ashok J. Chavan, Stefan Kruszewski, Stephen G. Zimmer, Kimberly A. Fraley, and Thomas G. BurkeView Author Information Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, Tigen Pharmaceuticals, Inc., Lexington, Kentucky 40506, and Division of Pharmaceutics Sciences, College of Pharmacy, Department of Microbiology and Immunology, College of Medicine, and Markey Cancer Center, University of Kentucky, Lexington, Kentucky 40506 Cite this: J. Med. Chem. 1999, 42, 16, 3018–3022Publication Date (Web):July 22, 1999Publication History Received6 May 1999Published online22 July 1999Published inissue 1 August 1999https://pubs.acs.org/doi/10.1021/jm9902279https://doi.org/10.1021/jm9902279rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views524Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anatomy,Lactones,Magnetic properties,Stability,Vesicles Get e-Alerts

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