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Effect of Lactobacillus rhamnosus strain GG (ATCC 53103) on the growth of Streptococcus sobrinus in vitro

1995; Wiley; Volume: 103; Issue: 4 Linguagem: Inglês

10.1111/j.1600-0722.1995.tb00169.x

1600-0722

Jukka H. Meurman, Heikki Antila, A. Korhonen, Seppo Salminen,

Microbial Metabolites in Food Biotechnology

Lactobacillus GG, a recently characterized L. rhamnosus GG strain (ATCC 53103), has been shown to exert inhibitory activity against a variety of bacterial species, including streptococci. We isolated and studied the effect of the inhibitory substance of Lactobacillus GG on some oral streptococci. The inhibitory activity of the isolated substance was weak, but some growth inhibition was observed in Streptococcus sobrinus pretreated with the substance in comparison with untreated controls. Zones of growth inhibition on agar plates were apparent only at pH values below 5, indicating that the inhibitory activity was restricted to a low pH range. Growth curve experiments showed a statistically significant inhibition between series with and without the isolated substance (P<0.05). The infrastructure of S. sobrinus was not affected when treated with the inhibitory substance. The Lactobadllus GG itself did not ferment sucrose. Thex