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Pathogenesis of Hereditary Emphysema and Replacement Therapy for α1-Antitrypsin Deficiency

1996; Elsevier BV; Volume: 110; Issue: 6 Linguagem: Inglês

10.1378/chest.110.6_supplement.248s

1931-3543

James E. Gadek, Eric R. Pacht,

Occupational and environmental lung diseases

The pathogenesis of emphysema and α1-antitrypsin deficiency are explored and the mechanisms of disease in α1-antitrypsin deficiency are then applied to more common forms of COPD, mainly cigarette smoke-induced emphysema. The pathogenesis of emphysema and α1-antitrypsin deficiency are explored and the mechanisms of disease in α1-antitrypsin deficiency are then applied to more common forms of COPD, mainly cigarette smoke-induced emphysema.