Artigo Revisado por pares

Hybrid Nanoparticles for Magnetic Resonance Imaging of Target‐Specific Viral Gene Delivery

2007; Volume: 19; Issue: 20 Linguagem: Inglês

10.1002/adma.200701952

ISSN

1521-4095

Autores

Yong‐Min Huh, Eun‐So Lee, Jae‐Hyun Lee, Young‐wook Jun, Pyung Hwan Kim, Chae‐Ok Yun, Ji Hoon Kim, Jin‐Suck Suh, Jinwoo Cheon,

Tópico(s)

Advanced biosensing and bioanalysis techniques

Resumo

Hybrid nanoparticles with multi-functional capabilities of targeted infection, magnetic resonance (MR) imaging, and gene delivery are developed by fusing virus and MnMEIO magnetic nanoparticles. Their successful utilizations for in vitro target-specific MR imaging and enhanced green fluorescent protein (eGFP) gene delivery into CAR-positive cells are demonstrated.

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