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BIBTEX RIS

Control of tubulin gene expression during metacyclogenesis of Trypanosoma cruzi

1986; Wiley; Volume: 208; Issue: 2 Linguagem: Inglês

10.1016/0014-5793(86)81053-5

1873-3468

Edson Rondinelli, Rodrigo S. Moura‐Neto, Rosane Suva, Célia Maria de Almeida Soares, José Francisco Carvalho, F. T. de Castro,

Research on Leishmaniasis Studies

During differentiation of the dividing epimastigote to the non‐dividing metacyclic trypomastigote form of the parasitic protozoan Trypanosoma cruzi there is a marked reduction in the rate of synthesis of the major proteins α‐ and β‐tubulin. Our results indicate that the control of synthesis of these proteins during the differentiation event is exerted at the level of α‐ and β‐tubulin mRNA accumulation.