Recommendations From the International Stroke Genetics Consortium, Part 2
2014; Lippincott Williams & Wilkins; Volume: 46; Issue: 1 Linguagem: Inglês
10.1161/strokeaha.114.006851
ISSN1524-4628
AutoresThomas W.K. Battey, Valerie Valant, Sylvia Baedorf Kassis, Christina Kourkoulis, Chaeyoung Lee, Christopher D. Anderson, Guido J. Falcone, Jordi Jiménez-Conde, Israel Fernández‐Cadenas, Guillaume Paré, Tatjana Rundek, Michael L. James, Robin Lemmens, Tsong-Hai Lee, Turgut Tatlisumak, Steven J. Kittner, Arne Lindgren, Farrah J. Mateen, Aaron L. Berkowitz, Elizabeth Holliday, Jennifer J. Majersik, Jane Maguire, Cathie Sudlow, Jonathan Rosand,
Tópico(s)Epigenetics and DNA Methylation
ResumoHomeStrokeVol. 46, No. 1Recommendations From the International Stroke Genetics Consortium, Part 2 Free AccessResearch ArticlePDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplemental MaterialFree AccessResearch ArticlePDF/EPUBRecommendations From the International Stroke Genetics Consortium, Part 2Biological Sample Collection and Storage Thomas W.K. Battey, BS, Valerie Valant, BA, Sylvia Baedorf Kassis, MPH, Christina Kourkoulis, BS, Chaeyoung Lee, PhD, Christopher D. Anderson, MD, MMSc, Guido J. Falcone, MD, ScD, MPH, Jordi Jimenez-Conde, MD, PhD, Israel Fernandez-Cadenas, MD, PhD, Guillaume Pare, MD, MSc, Tatjana Rundek, MD, PhD, Michael L. James, MD, Robin Lemmens, MD, PhD, Tsong-Hai Lee, MD, PhD, Turgut Tatlisumak, MD, PhD, Steven J. Kittner, MD, MPH, Arne Lindgren, MD, PhD, Farrah J. Mateen, MD, PhD, Aaron L. Berkowitz, MD, PhD, Elizabeth G. Holliday, PhD, Jennifer Majersik, MD, MS, Jane Maguire, PhD, Cathie Sudlow, DPhil and Jonathan Rosand, MD, MScon behalf of the International Stroke Genetics Consortium Thomas W.K. BatteyThomas W.K. Battey From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Valerie ValantValerie Valant From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Sylvia Baedorf KassisSylvia Baedorf Kassis From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Christina KourkoulisChristina Kourkoulis From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Chaeyoung LeeChaeyoung Lee From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Christopher D. AndersonChristopher D. Anderson From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Guido J. FalconeGuido J. Falcone From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Jordi Jimenez-CondeJordi Jimenez-Conde From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Israel Fernandez-CadenasIsrael Fernandez-Cadenas From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Guillaume PareGuillaume Pare From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Tatjana RundekTatjana Rundek From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Maguire); Division of Vascular Neurology, Department of Neurology, University of Utah, Salt Lake City (J. Majersik); School of Nursing and Midwifery, University of Newcastle, Newcastle, New South Wales, Australia (J. Maguire); and Division of Clinical Neurosciences and Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland (C.S.). , Michael L. JamesMichael L. James From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB—Vesalius Research Center, Experimental Neurology—Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales, Australia (E.G.H., J. Mag
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