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CCK-Containing paraneurons in human adenomatous prostate

1993; Portland Press; Volume: 13; Issue: 5 Linguagem: Inglês

10.1007/bf01137961

1573-4935

A Cecio, Tiziana Cocca, Martina Masotti, E. La Mura, Alfredo Vittoria,

Receptor Mechanisms and Signaling

The presence of CCK-containing neuroendocrine cells in human adenomatous prostates, and the colocalization of CCK together with serotonin in the same cell, have been demonstrated by means of an immunohistochemical technique and by a double labeling immunofluorescent staining. CCK-containing neuroendocrine cells had a focal distribution in the prostates and sometimes showed dendrite-like cytoplasmic processes. The major part of CCK (96.55%) colocalized with serotonin. CCK probably stimulates muscle contraction and endocrine/exocrine secretions in the urogenital tract.