Artigo Acesso aberto Revisado por pares

Quality of Life in Disease-Free Gastric Adenocarcinoma Survivors: Impacts of Clinical Stages and Reconstructive Surgical Procedures

2007; Karger Publishers; Volume: 24; Issue: 1 Linguagem: Inglês

10.1159/000100920

ISSN

1421-9883

Autores

Chi-Cheng Huang, Heng-Hui Lien, Pa‐Chun Wang, Jiao-Chiao Yang, Chan-Yeh Cheng, Ching-Shui Huang,

Tópico(s)

Nutrition and Health in Aging

Resumo

<i>Aim:</i> To investigate health-related quality of life data of disease-free gastric adenocarcinoma survivors, with special emphasis on the roles of clinical stages and reconstructive surgical procedures. <i>Methods:</i> We performed a cross-sectional study in 51 disease-free gastric adenocarcinoma patients. The patients had been followed for at least 6 (median 17, range from 6 months to 2 years) months after initial radical surgery. The Taiwan Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Cancer 30 (EORTC QLQ-C30) and the supplementary gastric cancer module QLQ-STO22 were used as outcome measures. <i>Results:</i> Patients with earlier-/advanced-stage diseases (American Joint Committee on Cancer stages I and II vs. III and IV) had a similar quality of life in terms of global health status and functional and symptomatic well-being. Subtotal gastrectomy outweighed total gastrectomy with better role function and less nausea/vomiting and appetite loss. Multivariate regression analyses also proved that proximal gastric preservation was predictive of better role function, less nausea/vomiting, and less appetite loss. <i>Conclusions:</i> Gastric adenocarcinoma survivors may enjoy a similar life quality, regardless of their original disease stages. Functional preservation may have marginal advantages to improve patients’ quality of life by reducing symptomatic nausea, vomiting, and appetite loss postoperatively.

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