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Generalized Malignant Acanthosis Nigricans

1979; American Medical Association; Volume: 115; Issue: 2 Linguagem: Inglês

10.1001/archderm.1979.04010020047014

1538-3652

George R. Mikhail,

Systemic Sclerosis and Related Diseases

We report a case of generalized malignant acanthosis nigricans (AN) secondary to metastasizing squamous cell carcinoma of the cervix uteri. The disease initially manifested in the perineum as condyloma acuminatum-like lesions. Subsequently, most of the cutaneous surface and the mucosa of the vulva, mouth, tongue, and the palpebral conjunctiva became involved. The association of AN with a squamous cell carcinoma is rare, and conjunctival involvement is unusual. ( Arch Dermatol 115:201-202, 1979)