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BIBTEX RIS

Novel Cell Culture Technique for Primary Ductal Carcinoma In Situ: Role of Notch and Epidermal Growth Factor Receptor Signaling Pathways

2007; Oxford University Press; Volume: 99; Issue: 8 Linguagem: Inglês

10.1093/jnci/djk133

ISSN

1460-2105

Autores

Gillian Farnie, Robert B. Clarke, Katherine Spence, N. Pinnock, Keith Brennan, Neil G. Anderson, Nigel Bundred,

Tópico(s)

Developmental Biology and Gene Regulation

Resumo

BackgroundThe epidermal growth factor receptor (EGFR) and Notch signaling pathways have been implicated in self-renewal of normal breast stem cells. We investigated the involvement of these signaling pathways in ductal carcinoma in situ (DCIS) of the breast.

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