Artigo Acesso aberto Produção Nacional Revisado por pares

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

2013; Elsevier BV; Volume: 123; Issue: 12 Linguagem: Inglês

10.1182/blood-2013-10-534743

ISSN

1528-0020

Autores

Ronan Desmond, Danielle M. Townsley, Bogdan Dumitriu, Matthew J. Olnes, Phillip Scheinberg, Margaret Bevans, Ankur R. Parikh, Kinneret Broder, Katherine R. Calvo, Colin O. Wu, Neal S. Young, Cynthia E. Dunbar,

Tópico(s)

Platelet Disorders and Treatments

Resumo

Key Points Eltrombopag promotes hematopoiesis in patients with severe aplastic anemia by stimulating stem and progenitor cells. Eltrombopag can be discontinued safely in robust responders with maintenance of hematopoiesis.

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