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Primary hepatic or hepatosplenic non-Hodgkin's lymphoma in children

1983; Wiley; Volume: 52; Issue: 12 Linguagem: Inglês

10.1002/1097-0142(19831215)52

1097-0142

Scott T. Miller, Norma Wollner, Paul A. Meyers, Philip R. Exelby, Berta Jereb, Denis R. Miller,

Chronic Lymphocytic Leukemia Research

CancerVolume 52, Issue 12 p. 2285-2288 ArticleFree Access Primary hepatic or hepatosplenic non-Hodgkin's lymphoma in children Scott T. Miller MD, Corresponding Author Scott T. Miller MD Department of Pediatrics, New York, New YorkMemorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021===Search for more papers by this authorNorma Wollner MD, Norma Wollner MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorPaul A. Meyers MD, Paul A. Meyers MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorPhilip Exelby MD, Philip Exelby MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorBerta Jereb MD, Berta Jereb MD Department of Radiation Therapy, Memorial Sloan-Kettering Cancer Center, New York, New YorkSearch for more papers by this authorDenis R. Miller MD, Denis R. Miller MD Department of Pediatrics, New York, New YorkSearch for more papers by this author Scott T. Miller MD, Corresponding Author Scott T. Miller MD Department of Pediatrics, New York, New YorkMemorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021===Search for more papers by this authorNorma Wollner MD, Norma Wollner MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorPaul A. Meyers MD, Paul A. Meyers MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorPhilip Exelby MD, Philip Exelby MD Department of Pediatrics, New York, New YorkSearch for more papers by this authorBerta Jereb MD, Berta Jereb MD Department of Radiation Therapy, Memorial Sloan-Kettering Cancer Center, New York, New YorkSearch for more papers by this authorDenis R. Miller MD, Denis R. Miller MD Department of Pediatrics, New York, New YorkSearch for more papers by this author First published: 15 December 1983 https://doi.org/10.1002/1097-0142(19831215)52:12 3.0.CO;2-KCitations: 41AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Non-Hodgkin's lymphoma confined to the liver is unusual in adults and has not been reported in children. Two children with primary hepatic and one with hepatosplenic NHL are described. All three patients are males, and both tumors examined for cell surface markers were of B-cell origin. Two patients, treated with chemotherapy and radiation, developed disseminated disease and died with 7 months of diagnosis. A third patient treated aggressively with radiotherapy and multiagent chemotherapy (LSA2–L2 protocol) remains in complete continuous remission 22 months after initiation of therapy. Hepatic NHL, even if well localized at diagnosis appears to warrant an aggressive therapeutic approach. Cancer 52:2285-2288, 1983. References 1 Roth A, Kolarie K, Dominis M. Histologic and cytologic liver changes in 120 patients with malignant lymphomas. Tumori 1978; 64: 45– 53. 2 Ata AA, Kamel IA. Primary reticulum cell sarcoma of liver. J Egyptian Med Assoc 1965; 48: 514– 521. 3 Carter JB. Macroglobulin producing histiocytic lymphoma of hepatic origin. Minn Med 1974; 57: 22– 24. 4 Chambers TJ, O'Donoghue DP, Stansfeld AG. A case of primary lymphoma of liver. J Clin Pathol 1965; 29: 967– 970. 5 Strayer DS, Reppun TS, Levin M, Deschryver-Kecskemeti K. Primary lymphoma of liver. Gastroenterology 1980; 78: 1571– 1576. 6 Talamo TS, Dekker A, Gurecki J, Singh G. Primary hepatic malignant lymphoma: Its occurrence in a patient with chronic active hepatitis, cirrhosis, and hepatocellular carcinoma associated with hepatitis B viral infection. Cancer 1980; 46: 336– 339. 7 Torres A. Primary lymphocytic follicular lymphoma of liver. Cancer 1969; 23: 1185– 1189. 8 Torres A, Bollozos G. Primary reticulum cell sarcoma of liver. Cancer 1971; 27: 1489– 1492. 9 Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extra-nodal lymphomas. Cancer 1972; 29: 252– 260. 10 Ziegler JL. Treatment results of 54 American patients with Burkitt's Lymphoma are similar to the African experience. N Engl J Med 1977; 297: 175– 180. 11 Wollner N, Wachtel A, Exelby PR, Centore D. Improved prognosis in children with intra-abdominal non-Hodgkin's lymphoma following LSA2L2 protocol chemotherapy. Cancer 1980; 45: 3035– 3039. Citing Literature Volume52, Issue1215 December 1983Pages 2285-2288 ReferencesRelatedInformation