Orbital granulocytic sarcomas (myeloid sarcomas) in acute nonlymphocytic leukemia
1992; Wiley; Volume: 70; Issue: 9 Linguagem: Inglês
10.1002/1097-0142(19921101)70
ISSN1097-0142
AutoresDurjoy K. Shome, Naresh Gupta, Nirmal Prajapati, Gottemukkala M.K. Raju, Panna Choudhury, Anand Prakash Dubey,
Tópico(s)Hematopoietic Stem Cell Transplantation
ResumoIn a series of 89 patients with acute leukemia, orbital granulocytic sarcomas were observed in 7. All these patients had acute nonlymphocytic leukemia, and they were all children. The orbital involvement usually was bilateral, and the patients had proptosis, conjunctival hemorrhage, and chemosis. Morphologic, cytochemical, and immunophenotypic analyses did not show a predilection for any particular myeloid cell type. Two patients had biphenotypic leukemias with myeloid components. The ocular manifestations responded well to chemotherapy irrespective of the hematologic response. Cancer 1992; 70:2298-2301.
Referência(s)