Reduction of isoquinoline and pyridine-containing heterocycles with lithium triethylborohydride (Super-Hydride®)
1993; Elsevier BV; Volume: 34; Issue: 45 Linguagem: Inglês
10.1016/s0040-4039(00)79297-5
ISSN1873-3581
AutoresBruce E. Blough, F. Ivy Carroll,
Tópico(s)Chemical Synthesis and Analysis
ResumoIsoquinolines, quinoline and pyridines are effectively reduced to 1,2,3,4-tetrahydroisoquinolines, 1,2,3,4-tetrahydroquinolines and piperidines respectively with lithium triethylborohydride (Super-Hydride®). The mechanism of the reduction was explored by reduction of isoquinoline and pyridine with lithium triethylborodeuteride (Super-Deuteride®).
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