Produção Nacional
Revisado por pares
Efficacy of ivermectin against the bloodsucking insect, Rhodnius prolixus (Hemiptera, Triatominae)
1985; Instituto Oswaldo Cruz, Ministério da Saúde; Volume: 80; Issue: 4 Linguagem: Inglês
10.1590/s0074-02761985000400009
ISSN1678-8060
AutoresPatrı́cia Azambuja, José Eugênio P. Lima Gomes, Fernando Lopes, Elói S. Garcia,
Tópico(s)Insect-Plant Interactions and Control
ResumoIvermectin (0.2 mg/kg body weight) caused a high mortality in nymphs and adults of Rhodnius prolixus following a single meal in mice sub-cutaneously injected with the drug. This effect was more evident in nymphs of 1st-and 2nd-instar than in older nymphs and adults. Third-instar nymphs presented a high mortality when fed on mice treated with ivermectin 24 and 48 hours previously, while mortality was significantly reduced in nymphs fed on mice treated 72 hours before. Surviving 3rd-instar nymphs did not molt. When adult females were fed once on mice treated for 24 hours with ivermectin there was a considerable reduction in egg production. This inhibition was not reversed by a second feeding on normal mice. We concluded that sub-lethal doses of ivermectin caused toxic effects interfering in the neuro-endocrine control of development and reproduction of this bloodsucking insect.
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